While I have never put together a list of my top ten favorite Doctor Who stories, The Doctor's Wife would make the list.
Before watching the episode, I was worried---after all, there was a lot of hype surrounding this one. People have high hopes for a Neil Gaiman written episode, and occasionally even the writing gods fail to love up to their standards (not that I am saying that Gaiman is a writing god, but some people seem to think that he is).
This story was a treat. It is one of those stories that take us to the very beginning of the series. This is going to be one of those episodes that die-hard fans are going to watch again and again, for it throws light on a lot of the mysteries of the series.
Reading the various reviews on the web of the episode, the one thing I have yet to see mentioned is the fact that the Tardis' energy appears to be the same as the regeneration energy. For those who have watched the entire season so far, think about where else we have seen these energies---is there a connection here that is still unclear?